Which of the following indicates a person has a Substance Use Disorder?

A person is considered to have a Substance Use Disorder when they display a pattern of behavior that leads to clinically significant impairment or distress. Specifically, the key indicator is the consistent use of a substance despite experiencing negative consequences or personal problems that arise from that use. This includes factors such as ongoing issues in personal relationships, job performance, or health concerns that are ignored because the individual continues to use the substance.

In contrast, infrequent use without consequences does not imply a disorder, as does using substances only in social settings, since those scenarios typically do not indicate a problematic pattern of use. Similarly, successfully managing work and personal life while using substances suggests a level of control and coping that would not classify as a Substance Use Disorder. Thus, the answer highlighting the continued use despite personal problems aligns directly with the diagnostic criteria for this condition.